{"status":"OK","data":{"advertisement":{"id":227292,"title":"Post\u0119powanie nr: DOTO/103/2023/01\n\u201eUs\u0142uga produkcji modyfikowanych chemicznie oligonukleotyd\u00f3w DNA\u201d\n\"Chemically modified DNA oligonucleotides production service \".","partial_offer_allowed":true,"publication_date":"2023-09-14","submission_deadline":"2023-10-16 23:59:59","planned_sign_date":"2023-10-01","supplementary_orders":"-","terms_of_contract_change":null,"created_at":"2023-09-14 17:46:05","modified_at":"2023-10-17 00:00:03","contact_persons":[{"id":58742,"forename":"Karolina","surname":"Miernik","phone_number":"","email":"k.miernik@dotomedical.com","created_by":null,"created_at":"2023-09-13 15:47:30","modified_at":"2023-09-13 15:47:30","modified_by":null}],"orders":[{"id":371760,"estimated_value":null,"order_items":[{"id":420172,"description":"DOTO/103/2023/01\nPrzedmiotem zam\u00f3wienia jest zakup us\u0142ugi produkcji i oczyszczania modyfikowanych chemicznie oligonukleotyd\u00f3w DNA (nazywanych jako aptamery) w tym: opracowanie procesu ich produkcji na pod\u0142o\u017cu sta\u0142ym oraz ich synteza i oczyszczanie w okre\u015blonej w zam\u00f3wieniu skali docelowej. Zam\u00f3wienie dotyczy projektu o numerze PB103, w ramach kt\u00f3rego zak\u0142ada si\u0119:\na.\tprodukcj\u0119 do 120 modyfikowanych chemicznie aptamer\u00f3w w docelowej skali 2 nanomoli,\nb.\tprodukcj\u0119 do 50 modyfikowanych chemicznie aptamer\u00f3w w docelowej skali 1 mikromola,\nc.\tprodukcj\u0119 do 4 modyfikowanych chemicznie aptamer\u00f3w  w docelowej skali 25 mikromola.\n\nThe subject of the order is the purchase of a service for the production and purification of chemically modified DNA oligonucleotides (called aptamers), including: development of their production process on a solid substrate and their synthesis and purification at the target scale specified in the order. The order concerns project number PB103, which assumes:\na.\tproduction of up to 120 chemically modified aptamers at a target scale of 2 nanomoles,\nb.\tproduction of up to 50 chemically modified aptamers at a target scale of 1 micromole,\nc.\tproduction of up to 4 chemically modified aptamers at a target scale of 25 micromoles.\n\nPakiet I/ Package I","warranty_period":null,"cpv_items":[{"id":8514,"code":"73110000-6","name":"Us\u0142ugi badawcze"}],"timetable_items":[],"fulfillment_places":[{"country":"Polska","voivodeship":"dolno\u015bl\u0105skie","poviat":"Wroc\u0142aw","commune":"Wroc\u0142aw-Fabryczna","locality":"Wroc\u0142aw","created_by":null,"created_at":"2023-09-14 17:46:05","modified_at":"2023-09-14 17:46:18","modified_by":null,"id":471708,"type":{"id":1,"name":"adres"},"group_uuid":"571e93f9-5c52-49ce-8b95-14ed2b4192ac"}],"participation_conditions":[{"id":1147010,"description":"Zamawiaj\u0105cy zastrzega, \u017ce oferty mog\u0105 z\u0142o\u017cy\u0107 wy\u0142\u0105cznie Oferenci, kt\u00f3rzy:\na.\tposiadaj\u0105 uprawnienia do wykonywania okre\u015blonej dzia\u0142alno\u015bci lub czynno\u015bci, je\u017celi prawo nak\u0142ada obowi\u0105zek ich posiadania do wykonywania dzia\u0142alno\u015bci obj\u0119tej zam\u00f3wieniem,\nb.\tposiadaj\u0105 przedstawiciela z wykszta\u0142ceniem biotechnologicznym do kontaktu z Zamawiaj\u0105cym, konsultowania i koordynowania zlece\u0144,         \nc.\tposiadaj\u0105 niezb\u0119dn\u0105 wiedz\u0119 i do\u015bwiadczenie w \u015bwiadczeniu us\u0142ug syntezy oligonukleotyd\u00f3w na pod\u0142o\u017cu sta\u0142ym oraz oczyszczaniu oligonukleotyd\u00f3w z wykorzystaniem technik PAGE i HPLC; \nd.\tposiadaj\u0105 niezb\u0119dn\u0105 wiedz\u0119 i do\u015bwiadczone w syntezie niestandardowych amidofosforyn\u00f3w (odpowiedniki nukleozyd\u00f3w u\u017cywane w syntezach na pod\u0142o\u017cu sta\u0142ym). \ne.\tposiadaj\u0105 mo\u017cliwo\u015bci techniczne do produkcji i oczyszczania chemicznie modyfikowanych oligonukleotyd\u00f3w w wymaganej skali.\n\n\nThe Ordering Party reserves that offers may only be submitted by Tenderers who:\na.\tare authorized to perform specific activities or activities, if the right imposes an obligation to have them to perform the activity covered by the contract,\nb.\thave a representative with biotechnology education to contact the Ordering Party, consult and coordinate orders,\nc.\thave the necessary knowledge and experience in providing oligonucleotide synthesis services on a solid substrate and purifying oligonucleotides using PAGE and HPLC techniques;\nd.\thave the necessary knowledge and experience in the synthesis of non-standard phosphoramidites (nucleoside equivalents used in solid-based syntheses).\ne.\thave the technical capabilities to produce and purify chemically modified oligonucleotides on the required scale.","type":{"id":4,"name":"Osoby zdolne do wykonania zam\u00f3wienia"},"created_by":null,"created_at":"2023-09-14 17:46:05","modified_at":"2023-09-14 17:46:18","modified_by":null,"group_uuid":"27619b8c-c69a-4986-bf57-38d02a9d8d5f"},{"id":1147011,"description":"1. Oferta musi by\u0107 z\u0142o\u017cona przez osob\u0119/osoby upowa\u017cnione.\n2. Oferta powinna zawiera\u0107 podpisane przez osoby upowa\u017cnione za\u0142\u0105czniki, przynajmniej:\na). dokument upowa\u017cniaj\u0105cy/upowa\u017cnienie dla osoby sk\u0142adaj\u0105cej ofert\u0119,\nb). za\u0142\u0105cznik nr 1 - uzupe\u0142niony formularz oferty wraz z o\u015bwiadczeniami dotycz\u0105cymi Oferenta, \nc). za\u0142\u0105cznik nr 2 - o\u015bwiadczenie o braku powi\u0105za\u0144 pomi\u0119dzy podmiotami wsp\u00f3\u0142pracuj\u0105cymi.\n3. Dopuszczalne jest podpisanie i z\u0142o\u017cenie oferty w formie elektronicznej.\n\n\n1. The offer must be submitted by an authorized person/person.\n2. The offer should contain attachments signed by authorized persons, at least:\nand). document authorizing/authorization for the person submitting the offer,\nb). Attachment No. 1 - completed offer form along with statements regarding the Bidder,\nc). Attachment No. 2 - statement on the lack of links between cooperating entities.\n3. It is acceptable to sign and submit an offer in electronic form.","type":{"id":6,"name":"Lista wymaganych dokument\u00f3w/o\u015bwiadcze\u0144"},"created_by":null,"created_at":"2023-09-14 17:46:05","modified_at":"2023-09-14 17:46:18","modified_by":null,"group_uuid":"96800e8b-3c57-4e1d-a5ff-d901aece5398"}],"category":{"id":1,"name":"Us\u0142uga"},"subcategory":{"id":8,"name":"Us\u0142ugi inne"},"created_by":null,"created_at":"2023-09-14 17:46:05","modified_at":"2023-09-14 17:46:18","modified_by":null,"group_uuid":"10f478f9-1041-4a0b-9273-92a1f701bb96"}],"evaluation_criteria":[{"id":639967,"price_criterion":true,"description":"Cena/ Price - 100%","created_by":null,"created_at":"2023-09-14 17:46:05","modified_at":"2023-09-14 17:46:18","modified_by":null,"group_uuid":"15b26530-d669-49f5-b50e-7e13446b05b2"}],"is_variant":false,"title":"Pakiet I","order_node":{"id":282489},"created_by":null,"created_at":"2023-09-14 17:46:05","modified_at":"2023-09-14 17:46:18","modified_by":null},{"id":371761,"estimated_value":null,"order_items":[{"id":420173,"description":"DOTO/103/2023/01\nPrzedmiotem zam\u00f3wienia jest zakup us\u0142ugi produkcji i oczyszczania modyfikowanych chemicznie oligonukleotyd\u00f3w DNA (nazywanych jako aptamery) w tym: opracowanie procesu ich produkcji na pod\u0142o\u017cu sta\u0142ym oraz ich synteza i oczyszczanie w okre\u015blonej w zam\u00f3wieniu skali docelowej. Zam\u00f3wienie dotyczy projektu o numerze PB103, w ramach kt\u00f3rego zak\u0142ada si\u0119:\na. produkcj\u0119 do 120 modyfikowanych chemicznie aptamer\u00f3w w docelowej skali 2 nanomoli,\nb. produkcj\u0119 do 50 modyfikowanych chemicznie aptamer\u00f3w w docelowej skali 1 mikromola,\nc. produkcj\u0119 do 4 modyfikowanych chemicznie aptamer\u00f3w w docelowej skali 25 mikromola.\n\nThe subject of the order is the purchase of a service for the production and purification of chemically modified DNA oligonucleotides (called aptamers), including: development of their production process on a solid substrate and their synthesis and purification at the target scale specified in the order. The order concerns project number PB103, which assumes:\na. production of up to 120 chemically modified aptamers at a target scale of 2 nanomoles,\nb. production of up to 50 chemically modified aptamers at a target scale of 1 micromole,\nc. production of up to 4 chemically modified aptamers at a target scale of 25 micromoles.\n\nPakiet II/ Package II\n\n","warranty_period":null,"cpv_items":[{"id":8514,"code":"73110000-6","name":"Us\u0142ugi badawcze"}],"timetable_items":[],"fulfillment_places":[{"country":"Polska","voivodeship":"dolno\u015bl\u0105skie","poviat":"Wroc\u0142aw","commune":"Wroc\u0142aw-Fabryczna","locality":"Wroc\u0142aw","created_by":null,"created_at":"2023-09-14 17:46:05","modified_at":"2023-09-14 17:46:18","modified_by":null,"id":471709,"type":{"id":1,"name":"adres"},"group_uuid":"deb3a5b3-ce15-4eb9-99da-b326c83fb698"}],"participation_conditions":[{"id":1147012,"description":"Zamawiaj\u0105cy zastrzega, \u017ce oferty mog\u0105 z\u0142o\u017cy\u0107 wy\u0142\u0105cznie Oferenci, kt\u00f3rzy:\na.\tposiadaj\u0105 uprawnienia do wykonywania okre\u015blonej dzia\u0142alno\u015bci lub czynno\u015bci, je\u017celi prawo nak\u0142ada obowi\u0105zek ich posiadania do wykonywania dzia\u0142alno\u015bci obj\u0119tej zam\u00f3wieniem,\nb.\tposiadaj\u0105 przedstawiciela z wykszta\u0142ceniem biotechnologicznym do kontaktu z Zamawiaj\u0105cym, konsultowania i koordynowania zlece\u0144,         \nc.\tposiadaj\u0105 niezb\u0119dn\u0105 wiedz\u0119 i do\u015bwiadczenie w \u015bwiadczeniu us\u0142ug syntezy oligonukleotyd\u00f3w na pod\u0142o\u017cu sta\u0142ym oraz oczyszczaniu oligonukleotyd\u00f3w z wykorzystaniem technik PAGE i HPLC; \nd.\tposiadaj\u0105 niezb\u0119dn\u0105 wiedz\u0119 i do\u015bwiadczone w syntezie niestandardowych amidofosforyn\u00f3w (odpowiedniki nukleozyd\u00f3w u\u017cywane w syntezach na pod\u0142o\u017cu sta\u0142ym). \ne.\tposiadaj\u0105 mo\u017cliwo\u015bci techniczne do produkcji i oczyszczania chemicznie modyfikowanych oligonukleotyd\u00f3w w wymaganej skali.\n\nThe Ordering Party reserves that offers may only be submitted by Tenderers who:\na.\tare authorized to perform specific activities or activities, if the right imposes an obligation to have them to perform the activity covered by the contract,\nb.\thave a representative with biotechnology education to contact the Ordering Party, consult and coordinate orders,\nc.\thave the necessary knowledge and experience in providing oligonucleotide synthesis services on a solid substrate and purifying oligonucleotides using PAGE and HPLC techniques;\nd.\thave the necessary knowledge and experience in the synthesis of non-standard phosphoramidites (nucleoside equivalents used in solid-based syntheses).\ne.\thave the technical capabilities to produce and purify chemically modified oligonucleotides on the required scale.","type":{"id":4,"name":"Osoby zdolne do wykonania zam\u00f3wienia"},"created_by":null,"created_at":"2023-09-14 17:46:05","modified_at":"2023-09-14 17:46:18","modified_by":null,"group_uuid":"5eae33af-59fb-414a-8467-665987aae735"},{"id":1147013,"description":"1. Oferta musi by\u0107 z\u0142o\u017cona przez osob\u0119/osoby upowa\u017cnione.\n2. Oferta powinna zawiera\u0107 podpisane przez osoby upowa\u017cnione za\u0142\u0105czniki, przynajmniej:\na). dokument upowa\u017cniaj\u0105cy/upowa\u017cnienie dla osoby sk\u0142adaj\u0105cej ofert\u0119,\nb). za\u0142\u0105cznik nr 1 - uzupe\u0142niony formularz oferty wraz z o\u015bwiadczeniami dotycz\u0105cymi Oferenta, \nc). za\u0142\u0105cznik nr 2 - o\u015bwiadczenie o braku powi\u0105za\u0144 pomi\u0119dzy podmiotami wsp\u00f3\u0142pracuj\u0105cymi.\n3. Dopuszczalne jest podpisanie i z\u0142o\u017cenie oferty w formie elektronicznej.\n\n\n1. The offer must be submitted by an authorized person/person.\n2. The offer should contain attachments signed by authorized persons, at least:\nand). document authorizing/authorization for the person submitting the offer,\nb). Attachment No. 1 - completed offer form along with statements regarding the Bidder,\nc). Attachment No. 2 - statement on the lack of links between cooperating entities.\n3. It is acceptable to sign and submit an offer in electronic form.","type":{"id":6,"name":"Lista wymaganych dokument\u00f3w/o\u015bwiadcze\u0144"},"created_by":null,"created_at":"2023-09-14 17:46:05","modified_at":"2023-09-14 17:46:18","modified_by":null,"group_uuid":"8aabc86c-9077-4dbf-b692-bd952720fda5"}],"category":{"id":1,"name":"Us\u0142uga"},"subcategory":{"id":8,"name":"Us\u0142ugi inne"},"created_by":null,"created_at":"2023-09-14 17:46:05","modified_at":"2023-09-14 17:46:18","modified_by":null,"group_uuid":"c8ff2de3-c677-43a8-9aad-b04eecaa43f4"}],"evaluation_criteria":[{"id":639968,"price_criterion":true,"description":"Cena/ Price- 100%","created_by":null,"created_at":"2023-09-14 17:46:05","modified_at":"2023-09-14 17:46:18","modified_by":null,"group_uuid":"bcfb2351-56c7-4f28-b6ae-5efaf34d7f0a"}],"is_variant":false,"title":"Pakiet II","order_node":{"id":282490},"created_by":null,"created_at":"2023-09-14 17:46:05","modified_at":"2023-09-14 17:46:18","modified_by":null},{"id":371762,"estimated_value":null,"order_items":[{"id":420174,"description":"DOTO/103/2023/01\nPrzedmiotem zam\u00f3wienia jest zakup us\u0142ugi produkcji i oczyszczania modyfikowanych chemicznie oligonukleotyd\u00f3w DNA (nazywanych jako aptamery) w tym: opracowanie procesu ich produkcji na pod\u0142o\u017cu sta\u0142ym oraz ich synteza i oczyszczanie w okre\u015blonej w zam\u00f3wieniu skali docelowej. Zam\u00f3wienie dotyczy projektu o numerze PB103, w ramach kt\u00f3rego zak\u0142ada si\u0119:\na. produkcj\u0119 do 120 modyfikowanych chemicznie aptamer\u00f3w w docelowej skali 2 nanomoli,\nb. produkcj\u0119 do 50 modyfikowanych chemicznie aptamer\u00f3w w docelowej skali 1 mikromola,\nc. produkcj\u0119 do 4 modyfikowanych chemicznie aptamer\u00f3w w docelowej skali 25 mikromola.\n\nThe subject of the order is the purchase of a service for the production and purification of chemically modified DNA oligonucleotides (called aptamers), including: development of their production process on a solid substrate and their synthesis and purification at the target scale specified in the order. The order concerns project number PB103, which assumes:\na. production of up to 120 chemically modified aptamers at a target scale of 2 nanomoles,\nb. production of up to 50 chemically modified aptamers at a target scale of 1 micromole,\nc. production of up to 4 chemically modified aptamers at a target scale of 25 micromoles.\n\nPakiet III/ Package III","warranty_period":null,"cpv_items":[{"id":8514,"code":"73110000-6","name":"Us\u0142ugi badawcze"}],"timetable_items":[],"fulfillment_places":[{"country":"Polska","voivodeship":"dolno\u015bl\u0105skie","poviat":"Wroc\u0142aw","commune":"Wroc\u0142aw-Fabryczna","locality":"Wroc\u0142aw","created_by":null,"created_at":"2023-09-14 17:46:05","modified_at":"2023-09-14 17:46:18","modified_by":null,"id":471710,"type":{"id":1,"name":"adres"},"group_uuid":"d9723685-9b21-4aed-baa4-4f435135a044"}],"participation_conditions":[{"id":1147014,"description":"Zamawiaj\u0105cy zastrzega, \u017ce oferty mog\u0105 z\u0142o\u017cy\u0107 wy\u0142\u0105cznie Oferenci, kt\u00f3rzy:\na.\tposiadaj\u0105 uprawnienia do wykonywania okre\u015blonej dzia\u0142alno\u015bci lub czynno\u015bci, je\u017celi prawo nak\u0142ada obowi\u0105zek ich posiadania do wykonywania dzia\u0142alno\u015bci obj\u0119tej zam\u00f3wieniem,\nb.\tposiadaj\u0105 przedstawiciela z wykszta\u0142ceniem biotechnologicznym do kontaktu z Zamawiaj\u0105cym, konsultowania i koordynowania zlece\u0144,         \nc.\tposiadaj\u0105 niezb\u0119dn\u0105 wiedz\u0119 i do\u015bwiadczenie w \u015bwiadczeniu us\u0142ug syntezy oligonukleotyd\u00f3w na pod\u0142o\u017cu sta\u0142ym oraz oczyszczaniu oligonukleotyd\u00f3w z wykorzystaniem technik PAGE i HPLC; \nd.\tposiadaj\u0105 niezb\u0119dn\u0105 wiedz\u0119 i do\u015bwiadczone w syntezie niestandardowych amidofosforyn\u00f3w (odpowiedniki nukleozyd\u00f3w u\u017cywane w syntezach na pod\u0142o\u017cu sta\u0142ym). \ne.\tposiadaj\u0105 mo\u017cliwo\u015bci techniczne do produkcji i oczyszczania chemicznie modyfikowanych oligonukleotyd\u00f3w w wymaganej skali.\n\n\nThe Ordering Party reserves that offers may only be submitted by Tenderers who:\na.\tare authorized to perform specific activities or activities, if the right imposes an obligation to have them to perform the activity covered by the contract,\nb.\thave a representative with biotechnology education to contact the Ordering Party, consult and coordinate orders,\nc.\thave the necessary knowledge and experience in providing oligonucleotide synthesis services on a solid substrate and purifying oligonucleotides using PAGE and HPLC techniques;\nd.\thave the necessary knowledge and experience in the synthesis of non-standard phosphoramidites (nucleoside equivalents used in solid-based syntheses).\ne.\thave the technical capabilities to produce and purify chemically modified oligonucleotides on the required scale.","type":{"id":4,"name":"Osoby zdolne do wykonania zam\u00f3wienia"},"created_by":null,"created_at":"2023-09-14 17:46:05","modified_at":"2023-09-14 17:46:18","modified_by":null,"group_uuid":"13cbedb9-b049-4338-9fc8-072c6c51ee9b"},{"id":1147015,"description":"1. Oferta musi by\u0107 z\u0142o\u017cona przez osob\u0119/osoby upowa\u017cnione.\n2. Oferta powinna zawiera\u0107 podpisane przez osoby upowa\u017cnione za\u0142\u0105czniki, przynajmniej:\na). dokument upowa\u017cniaj\u0105cy/upowa\u017cnienie dla osoby sk\u0142adaj\u0105cej ofert\u0119,\nb). za\u0142\u0105cznik nr 1 - uzupe\u0142niony formularz oferty wraz z o\u015bwiadczeniami dotycz\u0105cymi Oferenta, \nc). za\u0142\u0105cznik nr 2 - o\u015bwiadczenie o braku powi\u0105za\u0144 pomi\u0119dzy podmiotami wsp\u00f3\u0142pracuj\u0105cymi.\n3. Dopuszczalne jest podpisanie i z\u0142o\u017cenie oferty w formie elektronicznej.\n\n1. The offer must be submitted by an authorized person/person.\n2. The offer should contain attachments signed by authorized persons, at least:\nand). document authorizing/authorization for the person submitting the offer,\nb). Attachment No. 1 - completed offer form along with statements regarding the Bidder,\nc). Attachment No. 2 - statement on the lack of links between cooperating entities.\n3. 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